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Is metformin cheaper than insulin : study, and the drug was shown to actually provide benefits in diabetes Metformin – the "miracle cure" for diabetes has been around half a century. But new study found that a class of drugs, known as AT1221, may not provide any better results when it comes to diabetes. The results could impact how government prices these medications. A class of drugs developed and marketed by Gilead Sciences was recently added to the list of drugs covered by the Medicare Part D drug subsidy program under Obamacare. Part of this drug subsidy is a 10 percent rebate to doctors and drugs companies based on the cost effectiveness. Gilead Sciences has two drugs in the AT1221 class on market. Both metformin and its generic cousin, mirtazapine, have been shown in trials and clinical use to have significant benefits when compared to insulin alone. The drugs have been shown to decrease glucose levels in diabetes patients between 3 and 10 times better than insulin alone. Gilead Sciences has previously argued that using its drugs in combination with other medications like sulfonylureas, blood glucose-lowering drugs, or insulin has a larger effect because the additional medications work together better, but research suggests otherwise. The new research, published in England Journal of Medicine, found that Gilead Sciences' drugs did not improve glucose control when compared with the combination of insulin and metformin. The research was conducted on over 500 diabetes patients who were randomized to a placebo or metformin therapy. The study's lead author Prof. Robert Lustig, from the University of California San Francisco, explained the findings in an exclusive interview with IBTimes UK. "That was kind of a surprise. Our analysis suggested to me that, yes, there is no advantage to the combination of drugs," Lustig drugstore cowboy uk said. Lustig believes this study isn't the last word on issue yet, and that there is much more work to be done. "I think a lot more needs to be done because we've only looked at one class cheap ultram for sale of compounds in this study and we haven't looked at the other class," Lustig said. "What you Discount prescription card for phentermine need to know is, in what context am I taking this drug? And when you do that, what is your glycemic control like? What are the consequences of those in different situations? are the kinds of questions that researchers need to answer."

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